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Immune and Endocrine Function in Burnout Syndrome

From the Department of Health Psychology (P.M.C.M., L.J.P.v.D.), Utrecht University, Utrecht, The Netherlands; and the Laboratory for Psychoneuroimmunology (C.J.H., A.K.), University Medical Center Utrecht, Utrecht, The Netherlands.

View larger version (8K): [in this window] [in a new window]   Figure 1. Dexamethasone inhibition of T cell cytokine release. Whole blood samples were cultured in the presence of T cell mitogen phytohemagglutinin and increasing dexamethasone concentrations. Graphs show the mean and standard error of the burnout (•) and the control group () for (A) gamma interferon and (B) interleukin-10. Basal cytokine release in the absence of dexamethasone is shown in Table 4.

View larger version (8K): [in this window] [in a new window]   Figure 2. Dexamethasone regulation of monocyte cytokine release. Whole blood samples were incubated in the presence of lipopolysaccharide to stimulate monocyte cytokine release and increasing dexamethasone concentrations. Graphs show the mean and standard error of the burnout (•) and the control group () for (A) tumor necrosis factor alpha and (B) interleukin-10. Basal cytokine release in the absence of dexamethasone is shown in Table 4. *p < .05, **p < .01.