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Psychosomatic Medicine 33:265-278 (1971)
© 1971 American Psychosomatic Society

Relation of Psychologic Measures of Aggression and Hostility to Testosterone Production in Man

HAROLD PERSKY PhD1, KEITH D. SMITH MD2, and GOPAL K. BASU MSc2

1 Division of Endocrinology and Reproduction, Research Laboratories, Albert Einstein Medical Center, Philadelphia, Pa.; Recipient of Research Scientist Award 5K5-MH 18,374 from the National Institute of Mental Health of the US Public Health Service
2 Division of Endocrinology and Reproduction, Research Laboratories, Albert Einstein Medical Center Philadelphia, Pa.

Harold Persky, PhD, Albert Einstein Medical Center, Division of Endocrinology and Reproduction, Research Laboratories, York and Tabor Roads, Philadelphia, Pa 19141

Plasma testosterone level and testosterone production rate were determined in a group of 18 healthy young men, 15 healthy older men and 6 hospitalized dysphoric male patients. A battery of anxiety, depression and hostility tests were administered simultaneously. Production rate of testosterone was found to be highly correlated with a measure of aggression derived from the Buss-Durkee Hostility Inventory in the younger men. Age, on the other hand, was the principal correlant of production rate in the older group. A multivariate regression equation was obtained between testosterone production rate and four psychologic measures of aggression and hostility which accounted for 82% of the variance in the production rate of testosterone for the younger group. This equation was not valid for the older men.

Submitted on May 14, 1970
Revised on December 21, 1970




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